Patient portrayal. Individual results may vary.
Patient Profile
Meet Sarah, 45
- Has been seeing a therapist
- Family and colleagues have noticed she is still struggling
- In addition to her multiple MDD symptoms, she has been experiencing a slower pace when processing information
- Hoping to find overall relief from her MDD symptoms
MDD impacts more than just mood—it’s emotional, physical, and cognitive17
It’s critical to assess all the ways your patients are impacted by this multidimensional disease.18
EMOTIONAL
100% of patients report emotional symptoms
PHYSICAL
UP TO 90% of patients report physical symptoms
COGNITIVE
UP TO 94% of patients report cognitive symptoms
Beyond the multiple symptoms of MDD, Sarah is also experiencing problems with speed of processing.
What is Speed of Processing? 1,8
- It can be described as the pace at which a person can accurately process information
- Speed of processing is an aspect of cognitive function
- It may be impaired in patients with MDD
Brooke Kempf, PMHNP-BC
Psychiatric Mental Health Nurse Practitioner Hamilton Center, Terre Haute, Indiana
"As those of us who care for patients with MDD are aware, each patient’s experience can be different. It is important for patients and healthcare providers to have open and honest conversations.
If a patient like Sarah says "I’m okay," it is important to probe deeper and explore all of his or her potential symptoms of MDD."
Ms. Kempf began working at Hamilton Center, Terre Haute, Indiana in May 1995 as a Registered Nurse. She briefly left the organization in 2001 to continue her work as a Registered Nurse in the Behavioral Health Unit of Regional Hospital, but returned in 2002 where she works with patients with serious mental illnesses in multiple settings throughout the organization. In 2010, after receiving her Masters, she was promoted to a Psychiatric Nurse Practitioner where she works under Hamilton Center’s Chief Medical Officer to provide patient evaluations, diagnosis, and medication management for consumers with various serious mental illnesses. In addition, Ms. Kempf is an adjunct faculty member and Clinical Coordinator for IUPUI’s Psychiatric Mental Health Nurse Practitioner program. Ms. Kempf also enjoys providing education to other providers as a speaker for Takeda & Lundbeck, Alkermes, Otsuka, and Allergan Pharmaceuticals.
Ms. Kempf was paid as a consultant for Takeda and Lundbeck.
Jay Fawver, MD
Indiana University, Parkview Physicians Group Mind-Body Medicine, Fort Wayne, Indiana
"One important factor I consider when speaking with a patient with MDD is their social and occupational history. I use this information to discuss the symptoms of depression in terms the patient can better understand. I find this leads to more honest and productive conversations with patients."
Jay D. Fawver, MD, is the medical director at Parkview Mind‑Body Medicine in Fort Wayne, IN. At Mind‑Body Medicine, he orchestrates the treatment of over 8000 current patients in a shared pharmacological treatment model. He works with 10 nurse practitioners, assisted by nurses and medical assistants, utilizing customized electronic medical records to coordinate consistent clinical care with personalized and precision treatment strategies. His nurse practitioners provide integrated treatment by having access to direct consultation with Dr Fawver and the other nurse practitioners while utilizing treatment algorithms for various conditions and genetic profiles. Patients are monitored for treatment response and recovery utilizing patient-rated outcome metrics for mood, anxiety, cognition, insomnia, daily functioning, and side effects.
Since March 2020, Mind-Body Medicine has initiated telehealth for a majority of outpatients utilizing the new Epic Video Client internet platform. Utilizing this platform from their smartphones, tablets, or laptops, patients are prompted to complete outcome questionnaires on their MyChart portals 1 to 2 days prior to each appointment. These outcome metrics include the PHQ-9, GAD-7, Perceived Deficits Questionnaire (PDQ-20), Insomnia Severity Index (ISI), Work and Social Adjustment Scale (WSAS), and Patient Rated Inventory of Side Effects (PRISE), guiding treatment decisions and enhancing the efficiency of the outpatient video visit. Dr Fawver is a clinical professor of psychiatry at the Indiana University School of Medicine and is board certified by the American Board of Psychiatry and Neurology. He has been named a Distinguished Life Fellow of the American Psychiatric Association. A graduate of Purdue University School of Pharmacy, Dr Fawver was a pharmacist prior to his medical training. He has been an advisor to several pharmaceutical companies for over 30 years, participating as a principal investigator and assisting in the development of medication studies and outcomes of disease states such as depression, bipolar disorder, schizophrenia, and fibromyalgia with more recent work involving genetic correlations with medication treatment outcomes.
Since October 2019, Dr Fawver has been a certified Epic Physician Builder where he designs computer programs for charting in the electronic medical records based upon best practice guidelines.
Since 1997, he has been the host and producer of the Public Broadcasting System’s Matters of the Mind with Dr Jay Fawver, a weekly 30-minute live call-in television program addressing mental health topics.
Dr Fawver was paid as a consultant for Takeda and Lundbeck.
Michele Novella, APRN‑BC
Fairfield University, Medical Director and Owner of Star Psychiatric Healthcare, LLC, Danbury, Connecticut
"One symptom in particular that I find patients tend to misunderstand is anhedonia. For example, a patient may report that they are not experiencing pleasure in activities that they used to enjoy. Instead of identifying this as a symptom of depression, they may feel excessive guilt for this change, which is itself another symptom of MDD. I take this opportunity to remind my patients that, in people with MDD, these are symptoms of disease, not reflections of their character."
Michele Novella, APRN-BC, is the medical director and owner of Star Psychiatric Healthcare in Danbury, CT. She is a past member of Western Connecticut Health Network’s (WCHN) medical staff where she worked in the Behavioral Health Department including Crisis Intervention, Intensive Outpatient Program running groups and teaching Dialectical Behavioral Therapy (DBT). In the Outpatient setting, Michele held several critical incident debriefings following traumatic events and losses that were experienced by the staff there.
After graduating from Fairfield University, Michele worked as a Registered Nurse at Memorial Sloan-Kettering Cancer Center in New York City. Later, she worked at WCHN’s inpatient oncology unit before being asked to serve as Nurse Manager for the Outpatient Oncology & Chemotherapy Infusion Services at Associated Internists of Danbury. During that time, she received the prestigious American Cancer Society’s State‑Wide “Excellence in Oncology Nursing Award” in 1991.
Michele later pursued her Master’s Degree of Nursing from Yale University, graduating with Honors. She is Board Certified by the ANCC as both a Clinical Nurse Specialist in Adult Psychiatric Nursing, as well as a Psychiatric Nurse Practitioner.
She holds specialized training in DBT and cognitive behavioral therapy (CBT) and Critical Incident Stress Debriefing. She held a pivotal role in the aftermath of the Sandy Hook Shootings and helped to organize and run the crisis services offered to the public at Newtown’s Reed Intermediate School and treated several of the Newtown Police Department’s first responders. She has been asked to speak to several groups on post‑traumatic stress disorder and stress responses after trauma.
Ms Novella was paid as a consultant for Takeda and Lundbeck.
Gregory Mattingly, MD
Washington University, Midwest Research Group, St. Charles, Missouri
"When a provider puts the symptoms of depression in the context of the patient's life, we keep the conversation centered on how MDD affects them every day."
Dr Mattingly is a physician and principal investigator in clinical trials for Midwest Research Group. He is also a founding partner of St. Charles Psychiatric Associates, where he treats adults, adolescents, and children with ADHD. Dr Greg Mattingly is board-certified in adult and adolescent psychiatry and has been a principal investigator in over 300 clinical trials focusing on ADHD and related conditions.
Having served on numerous national and international advisory panels, Dr Mattingly has received awards and distinctions for clinical leadership and neuroscience research. He currently serves on the board of directors for the American Professional Society of ADHD and Related Disorders (APSARD).
Dr Mattingly was paid as a consultant for Takeda and Lundbeck.
Michele Novella, APRN‑BC
Fairfield University, Medical Director and Owner of Star Psychiatric Healthcare, LLC, Danbury, Connecticut
"When a patient comes to my practice experiencing symptoms of depression, an important part of my clinical evaluation will be to know the patient’s treatment history. As part of this, I make sure to ask my patients about any of their previous MDD treatments. In my clinical experience, MDD patients may need to try several treatments before finding the one that works for them, which might require follow‑up visits and calls. Knowing what the patient has tried and what they’re hoping to achieve allows me to make an informed treatment plan."
Michele Novella, APRN-BC, is the medical director and owner of Star Psychiatric Healthcare in Danbury, CT. She is a past member of Western Connecticut Health Network’s (WCHN) medical staff where she worked in the Behavioral Health Department including Crisis Intervention, Intensive Outpatient Program running groups and teaching Dialectical Behavioral Therapy (DBT). In the Outpatient setting, Michele held several critical incident debriefings following traumatic events and losses that were experienced by the staff there.
After graduating from Fairfield University, Michele worked as a Registered Nurse at Memorial Sloan-Kettering Cancer Center in New York City. Later, she worked at WCHN’s inpatient oncology unit before being asked to serve as Nurse Manager for the Outpatient Oncology & Chemotherapy Infusion Services at Associated Internists of Danbury. During that time, she received the prestigious American Cancer Society’s State‑Wide “Excellence in Oncology Nursing Award” in 1991.
Michele later pursued her Master’s Degree of Nursing from Yale University, graduating with Honors. She is Board Certified by the ANCC as both a Clinical Nurse Specialist in Adult Psychiatric Nursing, as well as a Psychiatric Nurse Practitioner.
She holds specialized training in DBT and cognitive behavioral therapy (CBT) and Critical Incident Stress Debriefing. She held a pivotal role in the aftermath of the Sandy Hook Shootings and helped to organize and run the crisis services offered to the public at Newtown’s Reed Intermediate School and treated several of the Newtown Police Department’s first responders. She has been asked to speak to several groups on post‑traumatic stress disorder and stress responses after trauma.
Ms Novella was paid as a consultant for Takeda and Lundbeck.